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论文实例中国人群进化与多基因病研究iiiiii

“outofafrica”model,multiregionalevolutionmodel,aswellassomemediationmodels.althoughtherearenotmanydivergencesintermsoftheoriginofhomoerectusamongthesehypothesis,thecontroversyontheoriginofhomos.sapieremai.onemodel,themultiregionalevolutionmodel,positsagradualtraitionfromhomoerectustoanatomicallymodernhumathroughouttheoldworld.incontrast,the“outofafrica”modelhypothesizesthatanatomicallymodernhumaarosefromasmall,isolatedpopulationinafrica,readoutofafrica,andreplacedindigenoush.erectuspopulatioineurasiaandaustralasia.whilemediationmodelhypothesizesthathomos.sapiearosefromthegeneticadmixtureofhomosapiewhichcamefromafricaaswellasthelocalones.plentyofpalaeoarchaeologicalfoilshavebeenfoundineastasia,eeciallyinchina,whichshowsdistinctivecontinuitytemporallyandmorphologically.therefore,eastasiahasbeenafocalpointinthestudyoforiginofmodernhuma.tosearchforevidenceofapoibleindependentoriginofmodernhumaninchina,9988maleindividualsweresampledacro

chinesemainlandantypedforthreeychromosomebiallelicmarker(m89,m130andyap)onthenonrecombinationofychromosome.resultbasedonourstudiespresentsthatalltheindividualscarryamutationatoneofthethreesites.thesethreemutatio(m89t,m130tandyap)coalescetoanothermutation(m168t),whichwasoriginallyderivedfromafrica,asnosingleindividualwasfoundthatcarriesalinkageolderthanm186toutsideafrica.inotherwords,allychromosomesamplesfromchina,withnoexception,wereoriginallyderivedfromalinkageofafricaorigin.hence,weconcludethatevenaveryminorcontributionofin-situhominido

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